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Building a healthier
and just
future for people who use drugs

Check our projects

Our services help with
and controlled

Syringe exchange

Drug testing service

Chemsex support


Outreach work

The core of Mainline's activities is outreach work. The outreach workers pick up signals on the street, in social shelters, near sex work and swing venues, in drug consumption rooms, in penitentiaries, at people who use at home, and online on relevant forums and apps. Because picking up signals and trends, informing, and referring, is only possible by being in direct contact with people who use drugs.


Chemsex combines sex and drugs. Mainline conducts long-term research on chemsex, develops informative materials, offers support to people who practice chemsex, and supports organisations in developing and implementing harm reduction interventions around chemsex.

Anabolic steroids

Mainline investigates the use of Performance and Image Enhancing Drugs (PIED) in recreational sports and develops harm reduction interventions and informative materials for athletes taking substances to improve performance and/or alter their physical appearance.

Projects we are most


Training: substances knowledge

Practical basic training on substances. This training is indispensable for professionals dealing with clients who use drugs.
  • Hands-on training
  • Deepen and expand your knowledge of drugs and use
More info

Training: overdose prevention

With this training, you will learn how to deal effectively with an overdose. With practical information and valuable tips.
  • Practical basic training
  • Tools to recognise and prevent overdose
More info

Training: making contact

Training on how to make contact with people who use drugs. Learn various communication techniques and enter the conversation confidently.
  • Practical basic training
  • Understand someone who uses
  • Various contact methods
More info


Stay up-to-date on the latest developments in drug policy, harm reduction, research and more.
Read more
new projects

Love Alliance Harare, Zimbabwe

new projects for English speakers


New manager: Ancella Voets

people who use drugs were reached

during outreach work in the Netherlands in 2022

0 %
of our GHB respondents

takes GHB to feel more confident

Indonesians who use drugs reached

with harm reduction programmes


Published four times a year, this lifestyle magazine for people who use drugs provides up-to-date information on developments in the drug scene.

More about the magazine